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KMID : 0378119790060010134
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Chungnam Medical Journal
1979 Volume.6 No. 1 p.134 ~ p.144
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Effect of K or Ca Supplement on Amino Acid Induced Insulin Response in Subjects with Furosemide Diuresis
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Abstract
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During Furosemide diuresis, amino acid induced-responses of plasma glucose, insulin and growth hormone concentration were measured in healthy men. Effects of potassium or calcium administration on the responses were also studied.
It was appeared that both the calcium or potassium supplement caused an alteration in amino acid induced responses shown during diuresis manifested by a increase in plasma insulin response and a decrease in plasma glucose rise. Although the increase in plasma insulin response after the ingestion of potassium were considerably greater than those that have been expected to result from the modest decreases observed in plasma sugar, furthur increase of insulin response after the calcium were consistent with decreased plasma suger.
It was suggested that extracellular potassium and calcium loss caused by abrupt diuresis might inhibit endogenous insulin response to amino acid stimulation.
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